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  4. Darya Vitalyevna Kazantseva

Darya Vitalyevna Kazantseva

Junior Researcher, Laboratory of Molecular Psychiatry

Division

Mental health research institute

Contact Information

E-mail: dashka1745@mail.ru
Tel.: +7 (3822) 72-38-29

Short Biography

Daria V. Kazantseva, born in 1998. In 2022, she graduated with honors from the Faculty of Medical Biology of the Siberian State Medical University (SibGMU) with a degree in "Medical Biochemistry". In the same year, she enrolled in full-time postgraduate studies (PhD program) at TNIMC in the specialty "Psychiatry and Narcology". Since 2023, she has been working as a Junior Researcher at the Laboratory of Molecular Psychiatry of the Mental Health Research Institute.

Research Interests

Biological psychiatry, schizophrenia and bipolar affective disorder, the study of catalytic antibodies (abzymes), molecular markers of mental disorders, proteomics, and mechanisms of oxidative stress.

Achievements and Awards

  • Laureate of the Presidential Scholarship of the Russian Federation for postgraduate students conducting scientific research within the framework of the priorities of scientific and technological development of the Russian Federation (2024).
  • Laureate of the Presidential Scholarship of the Russian Federation for students (2021) and the Government Scholarship of the Russian Federation (2019–2021) for excellence in studies and scientific activities.
  • Winner of the competition for the "Student of the Year" Award of the Tomsk Region Administration (2021).
  • Awarded the Honorary Badge "Future of the Tomsk Region" (Order of the Governor of the Tomsk Region dated 17.12.2021 No. 451-r-n).
  • Winner of the "Best Scientist of SibGMU" competition in the nomination "Best in Student Science" (2021).
  • Diplomas for the best oral and poster presentations at All-Russian and international conferences (including the N.I. Pirogov All-Russian Student Scientific Conference, the "NAUKA 0+" Festival, the Russian Conference "Modern Problems of Biological Psychiatry and Narcology", and the "Scientific Potential of the MHRI" competition).
  • Letter of Appreciation from TNIMC SB RAS for special merits and a significant contribution to the development of scientific research (2025)*.
  • Letter of Appreciation from SibGMU for a significant contribution to the development of scientific activities (2022).
  • Certificate of Merit from SibGMU for outstanding achievements in scientific activities (2021).

Participation in Grant Projects (as a Project Member / Co-investigator)

  1. RSF Grant No. 18-15-00053 "Search for peripheral markers associated with brain myelination impairment and disease pathogenesis in schizophrenia". Period: 2018–2020, extended to 2021–2022.
  2. RSF Grant No. 21-75-00071 "Proteolytic activity of catalytic antibodies in major endogenous mental disorders: prospects for differential diagnosis and prognosis assessment of schizophrenia and bipolar affective disorder". Period: 2021–2023.
  3. RSF Grant No. 23-75-00023 "Search for new molecular mechanisms of affective disorders to develop diagnostic and prognostic methods using proteomic approaches and neuroimaging". Period: 2023–2026.
  4. RSF Grant No. 23-75-10088 "The role of antioxidant enzymes and nitric oxide synthases in the mechanisms of metabolic syndrome formation in schizophrenia". Period: 2023–2026.

Key Publications

Daria V. Kazantseva is the author of over 50 scientific publications, including 10 full-text articles in peer-reviewed journals, 6 articles in scientific proceedings, 1 database registration certificate, and numerous conference abstracts.

  1. Kazantseva, D.V., Smirnova, L.P., Kornetova, E.G. et al. (2026). Hydrogen Peroxide Dismutation by Immunoglobulins G from Patients with Schizophrenia. Biochemistry (Moscow), 91, 1023–1033. https://doi.org/10.1134/S0006297926600456 (Q2 Web of Science, Q2 Scopus).
  2. Ermakov, E. A., Dmitrieva, E. M., Parshukova, D. A., Kazantseva, D. V., Vasilieva, A. R., Smirnova, L. P. (2021). Oxidative Stress-Related Mechanisms in Schizophrenia Pathogenesis and New Treatment Perspectives. Oxidative Medicine and Cellular Longevity, 2021. https://doi.org/10.1155/2021/8881770 (Q2 Web of Science, Q1 Scopus).
  3. Kamaeva, D. A., Smirnova, L. P., Vasilieva, S. N., Kazantseva, D. V., Vasilieva, A. R., Ivanova, S. A. (2022). Catalytic Antibodies in Bipolar Disorder: Serum IgGs Hydrolyze Myelin Basic Protein. International Journal of Molecular Sciences, 23(13), 7397. https://doi.org/10.3390/ijms23137397 (Q1 Web of Science, Q1 Scopus).
  4. Mednova, I. A., Smirnova, L. P., Vasilieva, A. R., Kazantseva, D. V., Epimakhova, E. V., Krotenko, N. M., Semke, A.V., Ivanova, S. A. (2022). Immunoglobulins G of Patients with Schizophrenia Protects from Superoxide: Pilot Results. Journal of Personalized Medicine, 12(9), 1449. https://doi.org/10.3390/jpm12091449 (Q2 Web of Science, Q1 Scopus).
  5. Yunusova, N. V., Popova, N. O., Udintseva, I. N., Klyushina, T. S., Kazantseva, D. V., Smirnova, L. P. (2023). The Role of Intravesicular Proteins and the Protein Corona of Extracellular Vesicles in the Development of Drug-Induced Polyneuropathy. Current Issues in Molecular Biology, 45(4), 3302-3314. https://doi.org/10.3390/cimb45040216 (Q2 Web of Science, Q2 Scopus).
  6. Kamaeva, D.A., Kazantseva, D.V., Boiko, A.S., Mednova, I.A., Smirnova, L.P., Kornetova, E.G., Ivanova, S.A. (2023). The Influence of Antipsychotic Treatment on the Activity of Abzymes Targeting Myelin and Levels of Inflammation Markers in Patients with Schizophrenia. Biomedicines, 11, 1179. https://doi.org/10.3390/biomedicines11041179 (Q1 Web of Science, Q1 Scopus).
  7. Epimakhova E.V., Smirnova L.P., Kazantseva D.V., Kamaeva D.A., Ivanova S.A. (2023). Different Directions of Effects of Polyclonal IgG Antibodies from Patients with Schizophrenia and Healthy Individuals on Cell Death In Vitro: A Pilot Study. Current Issues in Molecular Biology, 45(4), 3168-3179. https://doi.org/10.3390/cimb45040206 (Q2 Web of Science, Q2 Scopus).
  8. Parshukova, D.A., Buneva, V.N., Kornetova, E.G., Kazantseva, D.V., Vasilieva, A.R., Smirnova, L.P., Ivanova, S.A. (2019). Autoantibodies to Myelin Basic Protein in Patients with Schizophrenia Possess Proteolytic Activity. Russian Journal of Immunology, 13(22), No. 2, pp. 451-454. https://doi.org/10.31857/S102872210006927-4 (Q4 Scopus, VAK, RSCI) [in Russian].
  9. Smirnova, L.P., Epimakhova, E.V., Kazantseva, D.V., Kamaeva, D.A., Semke, A.V., Ivanova, S.A. (2023). Effect of Serum IgG from Schizophrenia Patients with Oxidoreductase Activities on Apoptosis Indicators in an In Vitro Experiment. Bulletin of Neurology, Psychiatry and Neurosurgery, No. 3, pp. 225-234. https://doi.org/10.33920/med-01-2303-07 (VAK, RSCI) [in Russian].
  10. Epimakhova, E.V., Smirnova, L.P., Kazantseva, D.V., Parshukova, D.A., Krotenko, N.M., Vasilieva, A.R., Ivanova, S.A., Semke, A.V. (2021). Evaluation of Cytotoxic Effects of IgG Isolated from the Blood Serum of Patients with Schizophrenia. Siberian Herald of Psychiatry and Addiction Medicine, No. 4 (113), pp. 5–13. https://doi.org/10.26617/1810-3111-2021-4(113)-5-13 (Q4 Scopus, VAK) [in Russian].
  11. Smirnova, L.P., Voronina, V.S., Antipina, P.A., Kazantseva, D.V., Kostromitsky, D.N., Yunusova, N.V. (2026). Catalase and SOD Activity of Serum Immunoglobulins G in Colorectal Cancer. Russian Journal of Immunology, No. 2, pp. 283-294 (Q4 Scopus, VAK, RSCI) [in Russian].